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Table 2 Predictive value of endocan in various medical conditions

From: The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses

Variable

Predictive value with 95% CI interval

heterogeneity

P value of Begg’s Publication bias

P value of Egger’s publication bias

Power

Diabetes mellitus

SMD 1.00, 95% CI 0.81–1.19, P < 0.01

62.19%

0.24

0.60

1-b = 1

Overall survival of Cancers

HR: 2.48, 95% CI: 2.12–2.90, P < 0.01

25.80%

Not reported

0.46

––––

Recurrence-free survival of cancers

HR: 2.08, 95% CI: 1.40–3.09, P < 0.01

0.00%

Not reported

0.37

––––

Hypertension

SMD: 0.91, 95% CI: 0.44–1.38, P < 0.01

95.43%

0.49

0.02

1-b = 1

Preeclampsia

SMD: 0.37, 95% CI: 0.13–0.62, P < 0.01

65.00%

Not reported

0.41

1-b = 0.99

Coronary artery disease

SMD: 0.99, 95% CI: 0.58–1.39, P < 0.01

89.8%

0.36

Not reported

1-b = 1

Coronary slow flow

SMD: 0.62, 95% CI: 0.45–0.78, P < 0.01

0.00%

0.66

Not reported

1-b = 1

Obstructive sleep apnea

SMD: 1.30, 95% CI: 1.06–1.54, P < 0.01

81.3%

Not reported

0.07

1-b = 1

Sepsis mortality

OR: 9.53, 95% CI: 3.34–27.3, P < 0.01

78.00%

Not reported

Not reported

1-b = 1

Sepsis multiple organ dysfunction syndrome

OR: 8.33, 95% CI: 2.07–33.58, P < 0.01

83.00%

Not reported

Not reported

1-b = 1

Sepsis respiratory failure

OR: 9.66, 95% CI: 2.26–43.95, P < 0.01

73.00%

Not reported

Not reported

1-b = 1

Chronic kidney disease

SMD: 1.34, 95%CI: 0.20–2.48, P < 0.01

98.32%

Not reported

Not reported

1-b = 1

COVID-19

SMD: 1.40, 95% CI: 0.21–2.58, P = 0.02

95.00%

Not reported

 > 0.05

1-b = 1

Acute respiratory distress syndrome

SMD: 0.47, 95% CI: 0.10–0.84, P = 0.01

 

Not reported

Not reported

1-b = 0.90