Table 1 Characteristics of included studies
From: The predictive value of endocan as a novel biomarker: an umbrella study on meta-analyses
First author name, year of publication | Journal | Searched databases | Date of search | Number of included studies | Total sample size | Outcome | Checklist used for quality assessment of included original studies | Funding status | Previous registered protocol | Model of analysis | AMSTAR 2 score |
|---|---|---|---|---|---|---|---|---|---|---|---|
Khalaji, 2023 [20] | Diabetology & Metabolic Syndrome | PubMed, Web of Science, Scopus, and Embase | February 13, 2023 | 24 | 3354 | Diabetes mellitus | Newcastle–Ottawa quality assessment scale | No | No | Random-effect meta-analysis | Low quality |
Huang, 2016 [21] | OncoTargets and Therapy | PubMed, Embase, and China National Knowledge Infrastructure | September 22, 2015 | 15 | 1,464 | Overall survival and recurrence-free survival of cancer | Newcastle–Ottawa quality assessment scale | Natural Science Foundation of China (81672869), National Science Foundation for Young Scholars (81,302,013), Jiangsu Provincial Science Foundation (BK20161596), and Jiangsu Provincial Six talent peak of Human affair Hall Funding (2013-WSW-037) | No | random-effect model or a fixed-effect model regarding the heterogeneity of the results | Low quality |
Behnoush, 2023[22] | Hypertension Research | PubMed, Scopus, Embase, and Web of Science | February 8, 2023 | 20 | 3130 | Hypertension | Newcastle–Ottawa quality assessment scale | Not reported | No | Random effect model | Low quality |
Lan, 2020 [23] | Bioscience Reports | PubMed and Embase | June 25, 2019 | 8 | 893 | Preeclampsia | Newcastle–Ottawa quality assessment scale | No funding | No | random-effect model or a fixed-effect model regarding the heterogeneity of the results | Low quality |
Zhao, 2018 [24] | Medicine (Baltimore) | PubMed, Embase, Cochrane Library, SinoMed, and Web of Science, | June 1, 2018 | 15 | 3097 | Coronary artery disease, coronary slow flow | Newcastle–Ottawa quality assessment scale | Hubei Provincial Department of Education (D20171201), Research Fund for Excellent Dissertation of China Three Gorges University (2017YPY060), and National Science Foundation of China grant (5281200) | No | random-effect model or a fixed-effect model regarding the heterogeneity of the results | Critically Low quality |
He,2023 [34] | Medicine (Baltimore) | PubMed, Cochrane Library, China National Knowledge Infrastructure, Web of Science, Embase, and Wan Fang database | January 2000 up to June 10, 2023 | 12 | 2199 | Obstructive sleep apnea | Newcastle–Ottawa quality assessment scale | Sichuan Medical Research Project Foundation (grant number: S21054) and Priming Scientific Research Foundation (CYFY-GQ59) | Prospero (CRD42023433137) | random-effect model or a fixed-effect model regarding the heterogeneity of the results | Low quality |
Behnoush, 2023 [37] | Angiology | PubMed, Embase, Web of Science, and Scopus | February 2023 | 7 | 1390 | Obstructive sleep apnea | Newcastle–Ottawa quality assessment scale | No funding | No | Random effect model | Low quality |
Fernández-Sarmiento, 2023 [38] | journal of intensive care medicine | Cochrane library, PubMed/MEDLINE, Embase, LILACS and Google Scholar | December 31, 2021 | 6 | 1,132 | sepsis | Newcastle–Ottawa quality assessment scale | No funding | Prospero (CRD42020217935) | random-effect model or a fixed-effect model regarding the heterogeneity of the results | Low quality |
Khalaji, 2023 [15] | Plos One | PubMed, Embase, Scopus, and Web of Science | February 13, 2023 | 20 | 2316 | Chronic kidney disease | Newcastle–Ottawa quality assessment scale | No funding | Prospero (CRD42023423593) | Random effect model | High quality |
Zhan, 2023 [35] | Therapeutic Advances in Respiratory Disease | PubMed, EMBASE, and the Cochrane Library | 1 December 2019 up to 18 May 2023 | 11 | 767 | Covid-19 | Newcastle–Ottawa quality assessment scale | National Natural Science Foundation of China (82373,643), Chongqing Talents: Exceptional Young Talents Project (CQYC202005003), Outstanding Youth Science Foundation of Chongqing (cstc2020jcyj-jqX0014), and the Science Foundation for Outstanding Young People of the Army Medical University | No | Random-effect model or a fixed-effect model regarding the heterogeneity of the results | Low quality |
Gaspar, 2022 [36] | Sleep Medicine Reviews | PubMed/Medline, Cochrane Library, Biblioteca Virtual da Saúde, Web of Science, EMBASE, World Intellectual Property Organization database, and bioRxiV and medRxiV Preprint Servers | May 31 st, 2020 | 16 | 2156 | Obstructive sleep apnea | Quality Assessment Tool for Diagnostic Accuracy Studies | European Regional Development Fund (ERDF), through the Centro 2020 Regional Operational Programme, under the project CENTRO-01–0145-FEDER-000012 (HealthyAging 2020); through the Operational Programme for Competitiveness and Internationalisation (COMPETE 2020) and Portuguese national funds via Fundaç ~ ao para a Ci^encia e a Tecnologia (FCT), under the projects POCI-01–0145-FEDER-029002 (noOSAnoAGEING, PTDC/MEC-MCI/29002/2017), UIDB/04539/2020, UIDP/04539/2020 and LA/P/0058/2020; and by the European Social Fund through the Human Capital Operational Programme (POCH) and Portuguese national funds via FCT under PD/BD/135497/2018, COVID/BD/152507/2022, 2020.04499.BD, and 2021.05334.BD | Prospero (CRD42020132556) | Random effect model | High quality |
Behnoush, 2024 [39] | Health Science Reports | PubMed, SCOPUS, Embase, and Web of Science | March 24, 2023 | 14 | 1058 | Acute respiratory distress syndrome | Newcastle–Ottawa quality assessment scale | No funding | No | Random effect model | Low quality |