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Table 2 Summary of eradication indications

From: A scoping review of worldwide guidelines for diagnosis and treatment of Helicobacter pylori infection

Indications/area (year)

Thailand 2015 [15]

Japan 2016 [18]

ASEAN 2018 [21]

America 2016 [17]

Brazil 2018 [19]

Egypt 2018 [20]

Korea 2020 [22]

Greece 2021 [25]

India 2021 [24]

China 2022 [30, 31]

Maastricht VI 2022 [28]

Long-term use of NSAIDs (including low-dose aspirin) and have a prior history of gastro-duodenal ulcers or bleeds

R

 

R

R

R

R

R

R

R

R

R

Peptic ulcer disease (prior history or active disease)

R

R

 

R

 

R

R

R

R

R

 

Gastric MALT Lymphoma

R

R

R

R

 

R

  

R

R

R

Unexplained iron deficiency anemia

 

R

  

R

 

R

R

R

R

R

Idiopathic thrombocytopenic purpura

 

R

 

R

R

 

R

R

R

 

R

Early gastric tumors have been treated

R

R

Rb

   

R

R

R

R

 

Uninvestigated dyspepsia

Rc

 

R

R

Ra

R

 

R

  

R

People at high risk of stomach cancer

R

 

R

R

 

R

 

R

 

R

 

Long-term use of PPIs

   

R

   

R

R

R

R

Idiopathic vitamin B12 deficiency

    

R

 

R

R

R

R

R

Helicobacter pylori infection was confirmed

   

R

 

R

   

R

 

Gastroesophageal reflux disease

NR

R

R

R

    

NR

  

Functional dyspepsia

 

R

    

R

R

   

Indications/area (year)

Saudi 2022 [27]

Italy 2022 [26]

Vietnam 2022 [29]

Indonesia 2022 [32]

Belgian 2023 [34]

Malaysia  2023 [35]

WGO 2023 [33]

Africa 2024 [36]

Germany 2024 [37]

ACG 2024 [39]

Recommended rate (n = 21)

Long-term use of NSAIDs (including low-dose aspirin) and have a prior history of gastro-duodenal ulcers or bleeds

R

R

R

R

R

 

R

R

R

R

19/21

Peptic ulcer disease (prior history or active disease)

R

 

R

R

R

R

R

R

R

R

17/21

Gastric MALT lymphoma

R

 

R

R

R

R

R

 

R

R

16/21

Unexplained iron deficiency anemia

R

R

R

R

R

 

R

 

R

R

15/21

Idiopathic thrombocytopenic purpura

R

 

R

R

R

 

R

 

R

R

14/21

Early gastric tumors have been treated

R

 

R

 

R

 

R

 

R

 

12/21

Uninvestigated dyspepsia

 

R

R

 

Ra

R

  

Ra

R

13/21

People at high risk of stomach cancer

R

 

R

  

R

R

 

R

R

12/21

Long-term use of PPIs

   

R

R

 

R

R

R

 

10/21

Idiopathic vitamin B12 deficiency

R

R

        

8/21

Helicobacter pylori infection was confirmed

R

     

Rd

R

R

R

8/21

Gastroesophageal reflux disease

R

R

R

R

  

R

 

NR

 

8/21

Functional dyspepsia

R

     

R

R

 

R

7/21

  1. NR not recommend, R recommended
  2. aThe original paper only mentioned dyspepsia
  3. bIncluding all gastric precancerous lesions
  4. cIndigestion where antisecretory drugs are ineffective
  5. dHelicobacter pylori eradication is determined according to the patient’s wishes