Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis

Zhang, Qiong; Duan, Jia; Zhang, Yuanmei; Yang, Lei; Li, Duo

doi:10.1186/s13643-025-02767-6

Systematic Reviews

Table 3 League table of separate analysis-treatment regimen

From: Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis

A. Separate analysis-treatment regimen of PFS
random.V1	random.V2	random.V3	random.V4	random.V5	random.V6	random.V7	random.V8	random.V9	random.V10	random.V11	random.V12
NCC							0.21 (0.09, 0.52)
0.53 (0.20, 1.38)	PTSC						0.40 (0.29, 0.56)
0.50 (0.19, 1.31)	0.95 (0.59, 1.52)	PNC					0.42 (0.30, 0.58)			0.25 (0.13, 0.47)
0.47 (0.18, 1.22)	0.89 (0.55, 1.42)	0.93 (0.58, 1.49)	NNC				0.45 (0.32, 0.63)
0.46 (0.18, 1.16)	0.87 (0.58, 1.29)	0.91 (0.61, 1.36)	0.98 (0.66, 1.46)	PPC			0.46 (0.37, 0.57)
0.44 (0.13, 1.48)	0.84 (0.36, 1.99)	0.89 (0.43, 1.82)	0.95 (0.40, 2.25)	0.97 (0.43, 2.21)	PTRC					0.28 (0.20, 0.40)
0.39 (0.15, 1.01)	0.75 (0.49, 1.14)	0.79 (0.52, 1.20)	0.84 (0.55, 1.28)	0.86 (0.62, 1.20)	0.89 (0.39, 2.04)	PDC	0.53 (0.41, 0.69)
0.21 (0.09, 0.52)	0.40 (0.29, 0.56)	0.42 (0.30, 0.58)	0.45 (0.32, 0.63)	0.46 (0.37, 0.57)	0.47 (0.21, 1.04)	0.53 (0.41, 0.69)	NC				0.48 (0.34, 0.69)
0.17 (0.06, 0.45)	0.32 (0.19, 0.54)	0.34 (0.20, 0.57)	0.36 (0.21, 0.61)	0.37 (0.23, 0.58)	0.38 (0.16, 0.92)	0.43 (0.27, 0.69)	0.80 (0.54, 1.20)	APC			0.60 (0.49, 0.73)
0.15 (0.06, 0.41)	0.29 (0.17, 0.48)	0.30 (0.18, 0.51)	0.32 (0.19, 0.55)	0.33 (0.21, 0.52)	0.34 (0.14, 0.83)	0.38 (0.24, 0.62)	0.72 (0.48, 1.08)	0.90 (0.68, 1.18)	AAC		0.67 (0.55, 0.82)
0.12 (0.04, 0.39)	0.24 (0.11, 0.52)	0.25 (0.13, 0.47)	0.27 (0.12, 0.59)	0.27 (0.13, 0.57)	0.28 (0.20, 0.40)	0.32 (0.15, 0.67)	0.59 (0.29, 1.21)	0.74 (0.33, 1.68)	0.83 (0.37, 1.87)	PC
0.10 (0.04, 0.27)	0.19 (0.12, 0.31)	0.20 (0.12, 0.33)	0.22 (0.13, 0.35)	0.22 (0.15, 0.33)	0.23 (0.10, 0.54)	0.26 (0.17, 0.40)	0.48 (0.34, 0.69)	0.60 (0.49, 0.73)	0.67 (0.55, 0.82)	0.81 (0.37, 1.79)	AC
B. Separate analysis-treatment regimen of OS
random.V1	random.V2	random.V3	random.V4	random.V5	random.V6	random.V7	random.V8	random.V9
PNC					0.43 (0.19, 0.98)
0.75 (0.26, 2.17)	NNC					0.57 (0.31, 1.07)
0.70 (0.27, 1.82)	0.93 (0.40, 2.15)	PTRC			0.62 (0.38, 1.01)
0.69 (0.26, 1.84)	0.92 (0.42, 2.02)	0.99 (0.48, 2.05)	PTSC			0.62 (0.39, 0.99)
0.58 (0.23, 1.45)	0.78 (0.39, 1.56)	0.84 (0.45, 1.56)	0.84 (0.48, 1.47)	PPC		0.73 (0.55, 0.98)
0.43 (0.19, 0.98)	0.58 (0.29, 1.14)	0.62 (0.38, 1.01)	0.63 (0.37, 1.07)	0.74 (0.50, 1.09)	PC	0.99 (0.77, 1.28)
0.43 (0.18, 1.01)	0.57 (0.31, 1.07)	0.61 (0.35, 1.06)	0.62 (0.39, 0.99)	0.73 (0.55, 0.98)	0.99 (0.77, 1.28)	NC		0.73 (0.51, 1.06)
0.32 (0.12, 0.84)	0.42 (0.20, 0.92)	0.45 (0.22, 0.93)	0.46 (0.24, 0.88)	0.54 (0.32, 0.93)	0.73 (0.44, 1.23)	0.74 (0.47, 1.16)	AAC	0.99 (0.77, 1.28)
0.31 (0.12, 0.80)	0.42 (0.20, 0.87)	0.45 (0.23, 0.87)	0.45 (0.25, 0.83)	0.54 (0.33, 0.86)	0.73 (0.46, 1.14)	0.73 (0.51, 1.06)	0.99 (0.77, 1.28)	AC
C. Separate analysis-treatment regimen of AD
random.V1	random.V2	random.V3	random.V4	random.V5	random.V6	random.V7	random.V8	random.V9	random.V10	random.V11
AC			0.73 (0.41, 1.28)					0.48 (0.34, 0.68)
0.91 (0.47, 1.77)	PC		0.80 (0.57, 1.14)		0.68 (0.46, 1.01)				0.48 (0.12, 1.89)
0.81 (0.40, 1.65)	0.89 (0.52, 1.54)	NNC	0.89 (0.59, 1.36)
0.73 (0.41, 1.28)	0.80 (0.57, 1.12)	0.89 (0.59, 1.36)	NC	0.98 (0.74, 1.31)		0.82 (0.56, 1.22)	0.73 (0.55, 0.97)		0.70 (0.47, 1.05)	0.36 (0.11, 1.15)
0.71 (0.38, 1.35)	0.78 (0.50, 1.22)	0.88 (0.53, 1.46)	0.98 (0.74, 1.31)	PDC
0.62 (0.28, 1.34)	0.68 (0.46, 1.01)	0.76 (0.39, 1.48)	0.85 (0.50, 1.44)	0.87 (0.48, 1.58)	PTRC
0.60 (0.30, 1.20)	0.66 (0.39, 1.10)	0.73 (0.41, 1.31)	0.82 (0.56, 1.22)	0.84 (0.51, 1.37)	0.97 (0.50, 1.86)	PTSC
0.53 (0.28, 1.00)	0.58 (0.37, 0.91)	0.65 (0.39, 1.08)	0.73 (0.55, 0.97)	0.74 (0.50, 1.12)	0.86 (0.47, 1.56)	0.89 (0.55, 1.44)	PPC
0.48 (0.34, 0.68)	0.52 (0.25, 1.11)	0.59 (0.27, 1.29)	0.66 (0.34, 1.29)	0.67 (0.32, 1.39)	0.77 (0.33, 1.81)	0.80 (0.37, 1.74)	0.90 (0.44, 1.87)	AAC
0.50 (0.25, 1.00)	0.55 (0.33, 0.91)	0.62 (0.35, 1.09)	0.69 (0.47, 1.02)	0.70 (0.43, 1.14)	0.81 (0.43, 1.54)	0.84 (0.48, 1.46)	0.94 (0.58, 1.53)	1.05 (0.48, 2.28)	PNC
0.26 (0.07, 0.96)	0.29 (0.09, 0.97)	0.32 (0.09, 1.11)	0.36 (0.11, 1.15)	0.37 (0.11, 1.22)	0.43 (0.12, 1.52)	0.44 (0.13, 1.50)	0.50 (0.15, 1.64)	0.55 (0.15, 2.10)	0.53 (0.16, 1.78)	NCC

A lower left HR/OR below 1 favors the column-defining treatment. The top right HR/OR is a direct comparison below 1 in favor of horizontal column treatment. Comparisons with differences of statistical significance (P < 0.05) are highlighted in bold format

Back to article page

ISSN: 2046-4053

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: journalsubmissions@springernature.com