Systematic review of the application of the Kidney Failure Risk Equation and Oxford classification in estimating prognosis in IgA Nephropathy

Table 4 Goodness-of-fit models for risk of ESRD at 5 years in total group and in subgroups based on baseline renal function

	Clinical models		Clinical and pathology models
Total (n = 1764)	Clinical model	CKD model	Limited model	Full model
C-statistic	0.90 (0.86–0.93)	0.90 (0.86–0.94)	0.91 (0.88–0.94)	0.91 (0.88–0.95)
AIC	453.14	450.11	441.26	440.24
R²	0.31	0.31	0.32	0.31
Subgroups (C-statistic)
eGFR < 60 (n = 589)	0.83 (0.78–0.88)	0.83 (0.79–0.88)	0.84 (0.80–0.89)	0.85 (0.81–0.89)
eGFR > 60 (n = 1175)	0.70 (0.52–0.89)	0.78 (0.62–0.95)	0.90 (0.84–0.97)	0.93 (0.87–0.99)

ESRD end-stage renal disease, eGFR estimated glomerular filtration rate (ml/min/1.73 m²), AIC Akaike information criterion. Higher values for C-statistic and R² indicate better models. Lower values for AIC indicate better models

ISSN: 2046-4053