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Table 2 Description of pharmacist interventions

From: The role of pharmacists in mitigating medication errors in the perioperative setting: a systematic review

Author (year)

Pharmacist intervention

Focus of the intervention

Recipients

Mode of contact

Methods of communication

Settings

Pharmacy contact (frequency)

Data source

Source guide for intervention

Supporting materials

AbuRuz et al. [33]

▪ Attending and discussing during medical rounds

▪ Follow-up of patient daily to resolve or prevent DRPs

▪ Discharge medication counselling

N/A

Patients

Contact with group (medical staff and patients)

▪ Face to face

▪ Hospital bedside

On or during patient admission, on discharge (continuous)

EMR

Up-to-date guidelines

None

Bansal et al. [38]

ESMOS services

▪ Patients are reviewed in a virtual pharmacist clinic whereby patients’ pre‐existing medical comorbidities are recorded along with any high‐risk medication the patient is taking

▪ In the postoperative phase, close monitoring on the ward with the focus being on medicines optimization to minimize the incidence of any postoperative complications occurring

▪ Collaboratively work in multidisciplinary teams

N/A

Patients

One on one

▪ Preadmission telephone

▪ Postadmission face to face

▪ Preadmission recipient home

▪ Postadmission

Hospital bedside

One time before admission and throughout the admission (continuous)

EMR

Always events toolkit by the NHS

None

Chen et al. [39]

▪ Quarterly lecture on rational use of PPIs to medical staff

▪ Rounds attendance and medication recommendations

▪ Interception of irrational PPI use

▪ Daily prescription audits and communicated with doctors and provides feedback

▪ Enlisting all essential monitoring drugs and checked medical records every month

▪ Monitoring of PPI-related ADR

PPI

Patients, medical staff

One on one (patient), contact with group (surgical team)

▪ Face to face, written

▪ Hospital bedside

On or during patient admission (continuous)

EMR

The PPIs Review Guidelines of the Second Affiliated Hospital of Fujian Medical University

None

Falconer et al. [40]

▪ Patient identification by surgery team

▪ Consultation to pharmacy (medication history documentation, documentation of patient preferred pharmacy, reconciliation of home and inpatient medications for hospital admission, recommend changes for medications as indicated, and provide patient education regarding proposed changes)

▪ Assigned clinical pharmacist to perform face-to-face inpatient consultation

▪ Standardized documentation and communication of recommendations with surgery team

N/A

Patients

Contact with group (medical staff and patients)

▪ Face to face

▪ Hospital bedside

On or during patient admission, on discharge (continuous)

EMR

Primary literature review, institutional expert opinion, drug information from databases

None

Fitzpatrick et al. [28]

▪ Review of electronic notes

▪ Phone call with patients to confirm history, demographics, answer patient’s questions, and involve patient in shared decision-making

▪ Discussion with the surgical team to highlight or resolve perioperative medical issues

▪ Individualized discharge prescription written, emailed, dispensed, and supplied to wards before patient admission

VTE prophylaxis, NSIADs, QTc prolonging medications

Patients

One on one (patient), contact with group (surgical team)

▪ Face to face, telephone, written

▪ Recipient home

1–2 weeks before admission, 7–10 days post discharge (twice)

NHS (VPN), (ARISE) dataset in Scotland

Evidence-based guideline produced in collaboration with surgical MDT team, health board guidance for VTE risk assessment and procedures

None

Hale et al. [34]

▪ Usual pharmacy care in addition to prescribing (continuing, discontinuing, and initiating medications with co-signature of physician

N/A

Patients and physicians

One on one

Face to face

Hospital (bedside and outpatient clinic)

Pre-operative (once)

Medication chart

Clinical guidelines and hospital VTE prophylaxis guidelines

None

Han et al. [41]

▪ A clinical pharmacist integration into the bariatric surgery clinic (as part of every patient’s preoperative clinic evaluation)

▪ A onetime 30- to 60-min meeting with the pharmacist prior to meeting with the surgeon

▪ Obtained medication histories and provided recommendations to patients and the team on perioperative medication management

▪ Resolved any potential DRP (e.g., medication absorption after bariatric surgery)

▪ Provided medication education to the patient

N/A

Patients

One on one

Face to face

Hospital (clinic)

Before admission (only once)

NR

NR

None

Kwan et al. [35]

Surgical Pharmacist in Preadmission Clinic Evaluation (SPPACE)

▪ Conducted a standardized comprehensive medication history interview and assessment focusing on the patient’s current home medication regimen in the preadmission clinic

▪ Description of any issue was written in the medical record to be considered by the surgeon

▪ Conducted telephone interviews with patients they were unable to see in the clinic

▪ After postoperative admission, verified with the patient if any medication changes had been made since the clinic assessment

N/A

Patients

One on one

Face to face or telephone if patient did not attend the clinic

Hospital (clinic), recipient home (by telephone) if patient did not attend the clinic

Before admission and postoperative admission, if possible (once or twice)

Patient history taking, if needed the pharmacist contacted community pharmacy or family physician

Not reported

Preprinted postoperative medication order form, EMR

Léguillon et al. [29]

▪ Medication’s review (within 72 h of admission)

▪ Pharmaceutical synthesis (summarized pharmaceutical plan with proposals)

▪ Dedicated meetings with geriatricians

N/A

Patients, geriatrician

One on one (patient, geriatrician)

Face to face

Hospital bedside

On or during patient admission (continuous)

EMR

STOPP/START, Medication appropriateness Index, French guideline

None

Luo et al. [30]

▪ Provide educational sessions and handouts about SUP for medical teams

▪ Collect information about the patient from the EMR and HIS

▪ Judge appropriateness of prophylactic acid suppressant use on: indication, selection, dose, duration of prophylaxis, combination, and replacement depending on the criteria

▪ Communicates immediately with the prescriber with their recommendation if any

▪ Report to the hospital administration every week

Omeprazole, lansoprazole

Physicians

One on one

Face to face

Hospital

On or during patient admission (as needed)

EMR

Hospital protocol

None

Marotti et al. [25]

▪ Document medication history or document medication history and prescribe

Beta-blockers, statins, antiplatelets, anticoagulant

Patients

One on one

EMR, telephone, fax

Hospital

Pre-operative (once)

EMR

Hospital protocol

None

Nguyen et al. [27]

▪ PREP pharmacist contacted patients via telephone 1 week prior to surgery to obtain BPMH and reconcile medications

▪ After surgery, a surgical pharmacist was provided with a handover from the PREP pharmacist for continuation of care

▪ The surgical pharmacist would verify the BPMH

▪ Confirmed MRF is generated by the pharmacist

▪ At discharge, the PREP pharmacist prepared discharge prescriptions for the patients, which is then checked and signed by the doctor

OTC products, cardiovascular medications, and analgesics

Patients

One on one

Telephone

▪ First contact: recipient home

▪ Second and third contact: hospital bedside

Before admission by the PREP pharmacist, on admission, and before discharge by the surgical pharmacist (three times)

NR

NR

Medication reconciliation form, EMR, handover form

SUREPILL Study Group [26]

▪ Medication reconciliation

▪ Consultation with the patient using a standard questionnaire

▪ Reviewing medication chart and optimizing medications when needed

▪ Performing interventions with liaison with the physician

▪ Weekly patient meetings (when possible)

▪ Reviewing discharge medications

▪ Patient counselling about the medications

N/A

Patients and physicians

One on one

Face to face

▪ Hospital

On or during patient admission, on discharge (continuous)

EMR & patient history taking

Hospital protocol

None

Van Prooyen et al. [36]

▪ Completion and documentation of a medication history

▪ Review of the home medication list for needed postsurgical medication changes

▪ Creation of a discharge medication plan based on a defined protocol

▪ Documentation of the recommended discharge medication plan in a consult note

▪ Patient education outlining the discharge medication plan

Extended release or other noncrushable formulations, NSAIDs, loop diuretics

Patients, surgeons

One on one (patient, Doctor)

Face to face, written, telephone

Hospital bedside

Post-operative day 1 (once, patient and as needed for physicians)

EMR

Institutional protocol based on guideline recommendation, primary literature review, drug information databases, and the team’s expertise

None

Yang et al. [42]

▪ Direct patient care and medication management during hospitalization

▪ Reviewing medication regimens, resolving DRPs and medication reconciliation

▪ Answering drug information questions

▪ Therapeutic drug monitoring (TDM)

▪ Making therapeutic recommendations

▪ Patient education

N/A

Patients

One on one (patient), contact with group (medical team)

Face to face

Hospital bedside

On or during patient admission (continuous)

Not reported

Not reported

None

Zhang et al. [37]

▪ Participation in daily medical rounds and clinical duties

▪ Targeted educational interventions for medical staff

PPI

Patients, medical staff

Contact with group (medical staff and patients)

Face to face

Hospital bedside

On or during patient admission (continuous)

EMR

Martindale: The Complete Drug Reference (39th), New Materia Medica, drug instructions, American Society of Health-System Pharmacists criteria and Expert consensus on the application of PPIs

None