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Table 3 Details on structure and findings for the NMAs, by outcome

From: Falls prevention interventions for community-dwelling older adults: systematic review and meta-analysis of benefits, harms, and patient values and preferences

 

Falls

Fallers

Injurious fallers

Fracture

Hip fracture

LTC

Functional status

HRQoL

RCTs

169

173

93

67

19

33

55

58

Total sample measuring outcome (% of total review sample = 167,864)

77,483 (46.2)

83,306 (49.6)

84,644 (50.4)

61,190 (36.5)

28,855 (17.2)

9640 (5.7)

12,185 (7.3)

25,442 (15.2)

RCTs with UC (N)

78 (45,369)

93 (57,911)

45 (67,741)

41 (47,291)

12 (20,405)

20 (7316)

26 (6077)

32 (9458)

RCTs with high risk of bias, (N)

42; 8297

35; 8402

16; 4175

16; 4175

1; 430

8; 2364

14; 2381

21; 4325

Total number of interventions/nodes

Disconnected nodesa, n (N)

57; 0

57; 0

49; 0

38; 0

19; 4 (930)

21; 2 (83)

33; 3 (812)

36; 6 (2130)

Average UC event rate (proportion)

1.15 per person

0.41

0.23

0.05

0.01

0.02

Not applicable

Not applicable

Certainty of evidence for benefit, n

High: 0

Moderate: 4

Low: 32

High: 0

Moderate: 18

Low: 9

High: 1

Moderate: 2

Low: 18

High: 1

Moderate: 1

Low: 17

High: 0

Moderate: 0

Low: 8

High: 0

Moderate: 0

Low: 10

High: 0

Moderate: 0

Low: 4

High: 0

Moderate: 0

Low: 3

Certainty of evidence for little-to-no difference, n

High: 0

Moderate: 0

Low: 11

High: 0

Moderate: 0

Low: 19

High: 0

Moderate: 0

Low: 15

High: 0

Moderate: 3

Low:1

High: 0

Moderate: 0

Low: 2

High: 0

Moderate: 0

Low:1

High: 0

Moderate: 0

Low: 14

High: 0

Moderate: 0

Low: 22

Certainty of evidence for harm (for benefit outcomes), n

High: 0

Moderate: 0

Low: 5

High: 0

Moderate: 2

Low: 3

High: 0

Moderate: 0

Low: 4

High: 0

Moderate: 1

Low: 6

High: 0

Moderate: 0

Low: 4

High: 0

Moderate: 0

Low: 8

High: 0

Moderate: 0

Low: 1

High: 0

Moderate: 0

Low: 2

Very low certainty (n due to no evidence)

6 (2)

7 (2)

18 (10)

28 (21)

44 (40)

39 (38)

39 (26)

31 (23)

  1. Abbreviations: HRQoL health-related quality of life, LTC long-term care, n number of nodes, N sample size, UC usual care, RCT randomized controlled trial
  2. aFor disconnected notes, the total number of studies by outcome are 2 (hip fracture), 1 (LTC), 5 (HRQoL), and 4 (functional status)