Table 1 Liver function tests of people with sickle cell disease in Africa
Authors | Setting | Study design | SCD/controls | Liver function |
|---|---|---|---|---|
Asaolu et al. 2010 | Ekiti, Nigeria | Prospective case-control study | 42/42 | ALP mean = 133.23, sd = 61.69; ALT mean = 28.68, sd = 9.85; AST mean = 20.42, sd = 10.94 [7] |
Obi et al. 2020 | Benin City, Nigeria | Prospective case-control study | 50/50 | ALT mean = 29.64, sd = 13.32; AST mean = 42.14, sd = 25.10 [21] |
Mohamed et al. 1992 | Khartoum, Sudan | Prospective case-control study | 84/28 | ALT mean = 93.37, sd = 37.95; AST mean = 37.70, sd = 21.50 [11] |
Akuyam et al. 2017 | Zaria, Nigeria | Prospective case-control study | 100/100 | ALP mean=108.8, sd = 5.40; ALT mean = 34.87, sd = 17.94; AST mean = 40.98, sd = 19.81 [19] |
Saha 1982 | Khartoum, Sudan | Prospective case-control study | 5/320 | ALT mean = 33.00, sd = 2.51; AST mean = 35.00, sd = 2.32 [20] |
Yahaya 2012 | Kano, Nigeria | Prospective case-control study | 150/100 | ALP mean = 82.67, sd = 10.87; ALT mean = 41.00, sd = 1.80; AST mean = 20.00, sd = 0.90 [22] |