Comparisons | Number of participants (studies) | Quality of the evidence (GRADE) | Anticipated mean difference (95% CI) |
---|---|---|---|
Low-level laser therapy (LLLT) vs conventional therapy (topical medication and placebo) | 121 (3 studies) | ⊕⊕◯◯ Low | − 2.55 [95% CI − 4.67, − 0.43]; I2 = 98% |
CO2 vs placebo | 70 (2 studies) | ⊕⊕⊕◯ Moderate | − 3.72 [95% CI − 4.18, − 3.25]; I2 = 0% |