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Table 1 Data variables for extraction and their definitions

From: The sequelae of hematopoietic stem cell transplantation in adolescents and young adults: protocol for a systematic review

Category

Variable

Definition

Publication specifications

Author(s)

First and last names of all authors

Date

Date of initial publication

Publication ID

PMID, doi, and/or ISSN

Journal

Name of journal where originally published

Database

Database source(s) from which the article was identified

Study characteristics

Design

Study design as defined by Campbell and Stanley (citation)

Aim

Objective of the study or primary research question it attempts to answer

Intervention

Exposure or treatment whose effect is being studied

Comparison

Defined group to whom the intervention is being compared, if applicable

Inclusion criteria

Subject characteristics necessary to be included in the study

Exclusion criteria

Subject characteristics that prevented inclusion in the study

Data source

Type of data that was collected and analyzed in the study (i.e., medical records, insurance databases, survey responses)

Study instruments

List any standardized scientific instruments used (i.e., PHQ-9 to measure depression)

Analysis

Planned statistical analysis described by study authors

Study setting

Location

Physical context for the study including facility (i.e., hospital vs. clinic) and geographic location (city, state, country)

Time

Period of time in which data was collected including start and end dates

Population

Larger group from which study subjects selected

Sample characteristics

Size

Number of subjects included in the study

Percentage AYA

Percentage of study subjects who were between 15 and 39 years old at the time of study inclusion

Age at diagnosis

Average age of cancer diagnosis among study subjects

Age at HSCT

Average age of HSCT among study subjects

Male sex

Percentage of study subjects who were male

Race/ethnicity

Distribution of races/ethnicities among study subjects

Insurance

Distribution of insurance coverage status among study subjects

Malignancy

Distribution of patients with leukemia, Hodgkin lymphoma, and non-Hodgkin lymphoma

Conditioning regimen

Distribution of various conditioning regimens used for HSCT

Outcomes

Primary outcome

The main finding of the study

Secondary outcomes

Additional study findings

Domain addressed

Which of the following conceptual domains were addressed in study outcomes: physical, psychological, social, spiritual, and health behaviors

Strengths

Author reported the strengths of the study

Limitations

Author reported the limitations of the study